Validation and comparison of a novel screening guideline for kidney disease: KEEPing SCORED.

the depression measure. Finally, Type D patients had a greater risk for cardiac death or MI compared with non– Type D patients (7 of 98 [7%] vs 5 of 239 [2%]; odds ratio, 4.84 [95% confidence interval, 1.42-16.52]; P=.01); depression was not related to this end point (P=.25). These findings show that Type D personality may have unique prognostic value beyond that of depressive symptoms. Only one-third of distressed patients with CAD had both a Type D personality and were depressed (28% had Type D personality and were nondepressed and 37% had a depressed and non–Type D personality), Type D personality was associated with a 3-fold increased risk of MACE, controlling for depression, and Type D personality but not depression predicted MACE, adjusting for disease severity. Another study also showed that Type D personality was associated with increased cortisol levels in patients with CAD, whereas depression as assessed by the BDI was not. Hence, Type D personality is more than just a marker of depression and should be assessed in its own right in patients with CAD.